Diffusion of Alexa Fluor 488-Conjugated Dendrimers in Rat Aortic Tissue
نویسندگان
چکیده
منابع مشابه
Diffusion of Alexa Fluor 488-conjugated dendrimers in rat aortic tissue.
In this study, the distribution of labeled dendrimers in native and aneurysmal rat aortic tissue was examined. Adult male rats underwent infrarenal aorta perfusion with generation 5 (G5) acetylated Alexa Fluor 488-conjugated dendrimers for varying lengths of time. In a second set of experiments, rats underwent aortic elastase perfusion followed by aortic dendrimer perfusion 7 days later. Aortic...
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We have discovered that the immunoreactivity of the fluorophore Alexa Fluor 488 survives glutaraldehyde and osmium tetroxide fixation and epoxy resin embedding and etching. We have developed new localization methods that for the first time take advantage of this property. The antigen is localized in cryosections using suitable primary antibody and an Alexa Fluor 488-conjugated secondary antibod...
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ژورنال
عنوان ژورنال: Annals of the New York Academy of Sciences
سال: 2006
ISSN: 0077-8923
DOI: 10.1196/annals.1383.004